EDUCATION:

Ph.D. Organic Chemistry, 1991, The Graduate School of the City University of New York (CUNY)
M.Phil. Organic Chemistry, 1991, The Graduate School, CUNY
M.A. Chemistry,1984, City College of New York, CUNY
B.S. Chemistry, 1981, Long Island University

COURSES TAUGHT:

Chemistry and the Arts (CH 103 and CH 104)
General Chemistry I (CH 151)
Organic Chemistry I and II (CH 251 and CH 252)

RESEARCH INTEREST

  • Total synthesis of several sesquiterpenes. We have recently synthesized two tricyclic sesquiterpenoid natural products sativene and longifolene via intramolecular cyclization of several cis-bromo-decalines. The synthetic protocol is employed toward another sesquiterpene natural product ylangene.
  • Synthesis of several linkers and head-groups in dequalinium salts.
  • Preparation and reaction of chiral oxycarbanions.

PUBLICATION

  • Allen Ko, Aaron Lam, Jeffrey Li, Edyta M. Greer, David J. Szalda, Sasan Karimi, Gopal Subramaniam, Keith Ramig, " Regioselective alkylation reactions of 2,4-diphenyl-3H-1-benzazepine give either 3-alkyl-3H-1-benzazepines or 1-alkyl-1H-1-benzazepines” Tetrahedron, 2014, 55, 4386-4389.
  • K. Ramig, E. M. Greer, D. J. Szalda, S. Karimi, A. Ko, L. Boulos, J. Gu, N. Dvorkin, H. Bhramdat, G. Subramaniam, "NMR Spectroscopic and Computational Study of Conformational Isomerism in Substituted 2 Aryl 3H 1-benzazepines: Toward IsolableAtropisomeric Benzazepine Enantiomers" J. Org. Chem. , 2013, 78, 8028-8036.
  • Sasan Karimi, Keith Ramig, Edyta M. Greer, David J. Szalda, William F. Berkowitz, Prakash Prasad, Gopal Subramaniam, "Tandem ring-contraction/decarbonylation of 2,4-diphenyl-3H-1-benzazepine to 2,4-diphenylquinoline” Tetrahedron, 2013, 69, 147-151.
  • Olga Lavinda, Irina Mironova, Sasan Karimi, Federica Pozzi, Jacopo Samson, Hiroko Ajiki, Lou Massa, Keith Ramig, "Singular thermochromic effects in dyeings with indigo, 6-bromoindigo, and 6,6’-dibromoindigo” Dyes and Pigments, 2013, 96, 581-589.
  • S. Karimi, A. Delgado, M. Lewinter, “A combinatorial/geometric analysis of parallelogram-like benzenoids” J. Math. Chem. 2012, 50, 904-913.
  • S. Karimi, A. Delgado, M. Lewinter, “A combinatorial/geometric analysis of convex cyclofusene” J. Math. Chem. 2010, 47, 167-173.
  • Keith Ramig, Edyta M. Greer, David J. Szalda, Rabail Razi, Fahima Mahir, Nataliya Pokeza, Wei Wong, Benjamin Kaplan, Joanne Lam, Ayesha Mannan, Christopher Missak, Dat Mai, Gopal Subramaniam, William F. Berkowitz, Prakash Prasad, Sasan Karimi, Ngai Hin Lo, Linas V. Kudzma, “Experimental and Theoretical Studies of a One-Flask Synthesis of 3H-1-Benzazepines from 2-Haloanilines and a,ß-Unsaturated Ketones” Eur. J. Org. Chem. 2010, 2363–2371.
  • G. Subramaniam, V. Patel, S. Karimi, “Conformational analysis of longifolene” Spectrosc. Lett. 2008, 41, 349-353.
  • S. Karimi, M. Lewinter, A. Delgado, “Resonance structure counts in parallelogram-like benzenoids with holes” J. Math. Chem. 2008, 44 (3), 913-916.
  • S. Karimi, M. Lewinter, S. Kalyanswamy, “Bilayered Cyclofusene” J. Math. Chem. 2008, 43 (2), 892-900.
  • S. Karimi, M. Lewinter, S. Kalyanswamy, “On the equitability of multiply-connected monolayered cyclofusene” J. Math. Chem. 2007, 41 (1), 59-61.
  • G. Subramaniam, S. Karimi, D. Phillips, “Solution conformation of longifolene and its precursor by NMR and ab initio calculations” Magn. Reson. Chem. 2006, 44, 1118-1121.
  • S. Karimi, J. Christodoulou, G. Subramaniam, “Tandem Favorskii Intermediate/Cyclization Leading to Tricyclo[4.4.0.0]decanediones” Synth. Commun. 2006, 36, 929-934.
  • S. Karimi, M. Lewinter, “On the properties of convex multilayered Cyclofusene” J. Math. Chem. 2006, 39 (3/4), 593-596. 
  • S. Karimi, M. Lewinter, “Interpolation of Shared p-Bonds in Cyclofusene”, J. Math. Chem. 2005, 38 (4), 103-106.
  • Dai, Z.; Proni, G.; Mancheno, D.; Karimi, S.; Berova, N.; Canary, J. W. “Detection of Zinc Ions byDifferential Circularly Polarized Fluorescence Excitation”J. Am. Chem. Soc.2004, 126, 11760-11761.
  • T. Bocchi, S. Karimi, M. Lewinter, “ On the Distribution of p Bonds in Cyclofusene”J. Math. Chem. 2004, 35, (4), 339-344.
  • S. Karimi, M. Lewinter, J. Stauffer, “Double Bonds in Fused Hexacyclic Systems”, J. Math. Chem. 2003, 34, 297-301.
  • S. Karimi, P. Tavares, “An Efficient Formal Synthesis of the sesquiterpenoid Longifolene”, J. Nat. Prod. 2003, 66, 520-523.
  • M. De Lezaeta, W. Sattar, P. Svoronos, S. Karimi, G. Subramaniam, “Studies on the Nature and Strength of Acids in the Pinacol Rearrangement using 1H NMR Spectroscopy”, Tetrahedron Lett. 2002,43, 9307-9309.
  • S. Karimi, D. Carrico, S. Anwar, “Tandem Ring Expansion/Aldol Cyclization of Bicyclo[5.4.0 1,7]Undecanediones”, Tetrahedron Lett. 2002, 43, 33-35.
  • S. Karimi, M. Lewinter, J. Stauffer, “Double Bonds in hexacyclic hydrocarbons and Maximal Planar Graphs”, Graph Theory Notes of New York 2002, 43, 9-11.
  • S. Karimi, “A Formal Total Synthesis of Sativene”, J. Nat. Prod. 2001, 64, 406-410.
  • S. Karimi, B. Petersen, K. Grohmann, M. Barnett, L. Todaro, “A Facile Entry into the Ring System of Sativene”, Tetrahedron Lett. 1998,39, 2689.
  • S. Karimi, K. Grohmann, L. Todaro, “Intramolecular Ring Opening of Cyclopropanones By Enolate Anion”, J. Org. Chem. 1995, 60, 554.
  • S. Karimi, K. Grohmann, L. Todaro, “Bromination and Dehydrobromination Studies on Some cis-4a-methyl-decaline-2,7-diones” Irn. J. Chem.& Chem. Eng. 1994,13,13.
  • S. Farnia, A. Kakanejadifard, S. Karimi, L. Todaro, “Synthesis and X-ray Structural Determination of 2,4,6,8-tetraphenyl-2,4,6,8-tetraazabicyclo-[3.3.0] octane”, Irn. J. Chem.& Chem. Eng. 1993,12,57

PRESENTATIONS

  • P. Chunmuang, G. Subramaniam, S. Karimi, “Interaction of chlorambucil analogs with DNA”.
  • V. Ling, S. Karimi, G. Subramaniam, P. Svoronos and D. Gao, “Tautomerization of heterocyclic organic molecules.”
  • S. Mobin, S. Karimi, “Preparation and Reactions of Chiral 2-Oxazolinyloxy and 2-Imidazolinyloxy-substituted carbanions.”
  • The research above is presented at the following conferences:
    • QCC’s 2nd Annual Honors Conference, April 28, 06.
    • The 54th  Undergraduate Research Symposium of the ACS-NY section at St. Johns University, April 29, 06.
  • L-A. Nelson, S. Mobin, S. Karimi, “Preparation and Reactions of Chiral 2-Oxazolinyloxy and 2-Imidazolinyloxy-substituted carbanions”. This work is presented at the following conferences:
  • QCC’s 1st Annual Honors Conference, April 15, 05.
  • The 53 rd Undergraduate Research Symposium of the ACS-NY section at Stony Brook, May 7, 05.
  • The 37 th Middle Atlantic Regional Meeting at Rutgers University, May 22-25, 05.
  • The ACS National Meeting, Washington D. C., Aug 28, 05.
  • J. Christodoulou, S. Karimi, “Total Synthesis of the Sesquiterpenoid Ylangene”, lecture at the 52 nd Annual UndergraduateResearch Symposium, Queensborough Community College, May 1, 2004.
  • Shinsung Lee, S. Karimi,“Relative Reactivity Ratios for the Chlorination of 3 o: 2 o:1 o Benzylic Hydrogens”, lecture at the 52 nd Annual UndergraduateResearch Symposium, Queensborough Community College, May 1, 2004.
  • J. Christodoulou, S. Karimi, “Total Synthesis of the Sesquiterpenoid Copaene”, Poster, Sigma Xi Research Society, Queens College Chapter, March 27 th 2003, 36th Middle Atlantic Regional Meeting (MARM) Spnsored by the Trenton ACS Section and Princeton University, June 9, 2003, and as a lecture at the 51 st Annual UndergraduateResearch Symposium, Long Island University, May 3, 2003, Poster, 226 th ACS National Meeting, New York, September 8, 2003.
  • A. Larkin, S. Karimi, D. Locke, G. Subramaniam, P. Svoronos, “Relative Reactivity Ratios for the Chlorination of 3 o:2 o:1 o Benzylic Hydrogens”, Poster, Sigma Xi Research Society, Queens College Chapter, March 27 th 2003, 36 th Middle Atlantic Regional Meeting (MARM) Spnsored by the Trenton ACS Section and Princeton University, June 9, 2003, and as a lecture at the 51 st Annual UndergraduateResearch Symposium, Long Island University, May 3, 2003, Poster, 226 th ACS National Meeting, New York, September 8, 2003.
  • D. Phillips, S. Karimi, G. Subramaniam, “ 1H and 13C NMR Assignments of a Tricyclic Terpene Precursor of Longifolene using 2D NMR Spectroscopy”, Poster, Sigma Xi Research Society, Queens College Chapter, March 27 th 2003, 36 th Middle Atlantic Regional Meeting (MARM) Spnsored by the Trenton ACS Section and Princeton University, June 9, 2003,and as a lecture at the 51 st Annual UndergraduateResearch Symposium, Long Island University, May 3, 2003, Poster, 226 th ACS National Meeting, New York, September 8, 2003.
  • P. Tavares, S. Karimi,“Total Synthesis of Longifolene”, 224 th ACS National Meeting, Boston, MA, submitted to Division of Chemical Education, August 18, 2002.
  • P. Tavares, S. Karimi,“Total Synthesis of Longifolene 50 th Symposium of the American Chemical Society for Undergraduate Research, Hofstra University, May 4, 2002.
  • M. Delezaeta, S. Karimi,P. Svoronos, The Pinacol Rearrangement: The Effect of Conjugate Base Presence on the Product Distribution”, 50 th Symposium of the American Chemical Society for Undergraduate Research, Hofstra University, May 4, 2002.
  • B. Alli, P. Svoronos, S. Karimi, P. Irigoyen, “A Solvolysis Study of Alkyl Halides Using Labworks II Interface: Solvent Effect on the Reaction Rate” 50 th Symposium of the American Chemical Society for Undergraduate Research, Hofstra University, May 4, 2002.
  • W. Sattar, S. Karimi, P. Svoronos, “The Pinacol Rearrangement: The Effect of Acid Nature and Concentration on the Product Distribution”50 th Symposium of the American Chemical Society for Undergraduate Research, Hofstra University, May 4, 2002.
  • D. Mancheno, S. Karimi, Z. Dai, J. Canary, “Synthesis and Physical Properties of the Chiral Tripodal Ligand 1-(2-Pyridylmethyl)-(2R, 6R)-Di(6-(2-Naphthyl)-2-Pyridyl)Piperidine, 50 th Symposium of the American Chemical Society for Undergraduate Research,Hofstra University, May 4, 2002.
  • P. Tavares, S. Karimi, “Total Synthesis of Longifolene”, Poster, Sigma Xi Research Society, Queens College Chapter, April 2002.
  • B. Tsun, P.Svoronos, P. Irigoyen, P. Tavares, S. Park, S. Karimi, “Solvolysis of Alkyl Halides-A StudyUsing LabWorks II Interface: Solvent Effect on the Kinetics of the Ionization Reaction”. Presented inform of a lecture at the New York Chemistry Students’ Association, ACS’S 49 TH AnnualUndergraduate Research Symposium, Pace University, May 5 2001.
  • P.Tavares, S. Karimi, P. Irigoyen, B. Tsun, S. Park, P. Svoronos. “Solvolysis of Alkyl Halides-A Study Using LabWorks II Interface: Comparative Measurement of Reaction Rates For Different Alkyl Halides.” Presented in form of a lecture at the New York Chemistry Students’ Association, ACS’S 49 TH Annual Undergraduate Research Symposium, Pace University, May 5 2001.
  • S. Karimi, S. Anwar, “Intramolecular Self-Aldol Condensation”, Poster, CUNY Conference in Science & Engineering, 2001.

ACADEMIC AND PROFESSIONAL HONORS

  • Delivered the Presidential Lecture Series-QCC, entitled “The Art of Chemistry and the Chemistry of Art”, March 29, 06.
  • Delivered a lecture for the monthly seminars of the Long Island Section of the American Chemical Society, entitled “Chemistry and Art”, December 7, 2006
  • Chair of the New York-Long Island subsection of the American Chemical Society 2005-2006.
  • Oral presentation for Project based learning for the Fall Faculty Meeting, Second Conference of the College at QCC, Nov 19, 04.
  • Serving as a Faculty Advisor on the Committee for The ACS Annual Undergraduate Research Symposium (AURS), 2000-present.
  • Elected councilor for the New York Section of the American Chemical Society (ACS), 2003-2005.
  • Elected to serve as Director-at-Large in the New York Section of the American Chemical Society (ACS), 2000. This is a local ACS section with over 5,000 professional members.
  • Selected by the American Chemical Society to participate in the Shaping the Preparation of Future Science and Mathematics Faculty program. This effort was acknowledged by the President of the Association of American Colleges and Universities, President of the Council of Graduate School, and the President of QCC.

GRANTS

  • Recipient of the PSC-CUNY 37 award entitled “Synthesis and investigation of optically active alkoxy-oxazolines and alkoxy-imidazolines”. The award is in the amount of $1,800 for one year beginning July 1, 2006
  • Recipient of the PSC-CUNY 36 award entitled “ Synthesis and investigation of optically active alkoxy-oxazolines”. The award is in the amount of $1,700 for one yearbeginning July 1, 2005.
  • The Eppley Foundation for Research award entitled: “Preparation and reaction of chiral oxycarbanions”. The award is in the amount of $21,017 for one year 2005-2006.
  • PSC-CUNY Collaborative Incentive Grant entitled, "Lysophospholipids: Synthesis of Stereoisomers and Activity on Their Receptors”, two year period, March 1, 2003-February 28, 2005. The award amount is $48,726 per year for two years.
  • GRTI (graduate research teaching initiative) award entitled: “Circular Dichroism Investigations of Synthesis of Small Molecules and Binding to Proteins and Nucleic Acids”. This grant was participated by: Professors. Thomas C. Strekas and Prof. Susan Rotenberg of Queens College, and Prof. Sasan Karimi of Queensborough. The CD equipment will be purchased and housed at Queens College.The award is in the amount of $55,000, Fall 2002.
  • CUNY Faculty Development Program Proposal entitled “Chemistry and the Arts: Two Years after Instituting the Course”. The award is in the amount of $2,560 for one year 2002-2003.
  • PSC-CUNY award entitled PSC/CUNY 33 “Development and Biological Characterization of Dequalinium Analogues as PKC Inhibitors,” The award is in the amount of $4,500 for one year 2002-2003.
  • PSC-CUNY award entitled PSC/CUNY 32 “An Approach Toward a Total Synthesis of Longifolene”, The award is in the amount of $4,325 for one year 2001-2002.
  • PSC-CUNY award entitled a) Total Synthesis of Sativene b) An Entry into the Ring System of Longifolene. The award is in the amount of $3,068 for two years, 1999-2001.
  • PFF (Preparing Future Faculty) award made to Queens College, administered by the American Chemical Society. I was the liaison from QCC as one of the collaborative colleges in the application for a PFF grant submitted by Queens College. The award is for $18,300 for two years, Fall 1999-Spring 2000.
  • CUNY Faculty Development Program Proposal entitled: "Using Chemistry in the Restoration of Artifacts". This proposal was approved for the total budget of $2,740, Fall 1999.
  • CUNY Research Foundation for purchase of research equipment. This proposal was approved for the total budget of $15,000, 1999.

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